Extracorporeal blood oxygenation and ozonation (EBOO)
What is EBOO?
EBOO is an advanced ozone therapy modality that circulates a large volume of a patient’s blood (1.5–3 L, nearly half the body’s total) through a closed dialysis-like filter system. While ozonating the blood with an oxygen‑ozone mixture, it simultaneously filters out debris, toxins, and metabolic byproducts—then returns the purified, oxygen-rich blood back to the body
How does EBOO work?
Blood is withdrawn through one vein, passed through a sterile dialyzer where it’s infused with controlled ozone and oxygen mixture, and filtered across a membrane before being returned via another vein. This process typically lasts 60–90 minutes and treats several liters of blood, maximizing circulation, oxygen delivery, detoxification, and immune activation
Benefits of EBOO Therapy
1. Enhanced Oxygenation & Circulation
- Significantly improves tissue oxygen delivery and red blood cell flexibility, boosting mitochondrial function and energy production.
- Supports cardiovascular health by reducing ischemia and improving microcirculation.
2. Immune System Activation & Pathogen Reduction
- Stimulates white blood cell function and activates NRF2 antioxidant pathways .
- Demonstrated antibacterial, antifungal, antiviral, and antiparasitic effects.
3. Potent Anti-Inflammatory Effects
- Reduces systemic and localized inflammation by inducing controlled oxidative stress and upregulating antioxidant defenses.
4. Effective Detoxification & Filtration
- Operates like ozone dialysis: filters up to 2–3 L of blood, removing cellular debris, microclots, heavy metals, and toxins.
5. Pain Relief & Tissue Regeneration
- Aids in recovery from musculoskeletal injuries, chronic pain, and peripheral artery ischemia/responsive conditions.
6. Cognitive Boost & Emotional Clarity
- Enhances mental clarity and reduces brain fog through improved oxygenation and detoxification.
7. Support in Complex Chronic Conditions
- Used to help manage autoimmune issues, chronic infections (e.g., Lyme, mold, long COVID), fibromyalgia, and chronic fatigue syndrome.
8. Adjunct to Cancer Care & Wound Healing
- Supports cancer treatments by enhancing oxygenation and immunity; promotes wound healing via improved circulation and antimicrobial action
Watch the Extracorporeal blood oxygenation and ozonation (EBOO) Video
Frequent Question Answer (FAQ)
When administered correctly by trained professionals, EBOO in a closed-filter system is generally safe. However, individuals with bleeding disorders, pregnant women, or those on blood thinners should consult a physician
Approximately 60–90 minutes of blood circulation and ozonation, plus pre‑ and post-procedure prep—totaling about 2 hours
A typical protocol includes 3 sessions spaced 1–2 weeks apart, with maintenance monthly or quarterly. Chronically ill individuals may require more frequent treatments initially
The procedure uses IV access; most clients remain comfortable, with possible mild warming or fatigue post-treatment.
Mild fatigue, transient headache, or slight fever may occur as the body initiates detoxification. Serious adverse events are rare with proper protocols
It’s generally suitable for adults seeking therapeutic detoxification or support for chronic conditions. Exclusions apply for those pregnant, on anticoagulants, with G6PD deficiency, or recent bleeding events
Yes—see above. Additionally, severe cardiovascular instability or anemia may require evaluation.
EBOO delivers 3–4× more ozone to blood than multi-pass ozone IV or major autohemotherapy and adds filtration, making it more efficient and comprehensive
Filtration may eliminate debris, microplastics, heavy metals, and pathogens. Although anecdotal, clinical follow-ups show improvements in inflammatory markers and toxin-related symptoms
In the U.S., single sessions range from ~$900–1,500, with package deals for 3–5 sessions. Some clinics charge up to $3,800 per treatment .
